Artículos Científicos

Publicaciones 1999-2019

1. Castillo H C, Sanhueza H L, Täger F M, Muñoz N S, Ossa A G, Vial C P. Prevalencia de anticuerpos anti-hantavirus en 10 comunas de la Novena Región de Chile donde se han diagnosticado casos de infección clínica por hantavirus. Revista médica de Chile. 2002 2002-03;130(3):251-8. PubMed PMID: SCIELO:S0034-98872002000300002.
2. Galeno H, Mora J, Villagra,E, Fernandez J, Hernandez J, Mertz G, Ramirez E, First Human Isolate of Hantavirus (Andes virus) in the Americas Emerging Infectious Disease, 2002, Jul; 8 (7) 657-661
3. Castillo H C, Cea B X, Navarrete C M, Ossa A G. Neumonías atípicas graves y diagnóstico diferencial con el síndrome cardiopulmonar por hantavirus. Experiencia clínica en tres casos confirmados. Revista chilena de enfermedades respiratorias. 2003 2003-04;19(2):101-8. PubMed PMID: SCIELO:S0717-73482003000200006.
4. Täger Frey M, Vial PC, Castillo CH, Godoy PM, Hjelle B, Ferrés MG; Hantavirus prevalence in the IX Region of Chile. Emerg Infect Dis. 2003 Jul;9(7):827-32.PubMed PMID:12890323
5. Castillo C, Villagra E, Sanhueza L, Ferres M, Mardones J, Mertz GJ. Prevalence of antibodies to hantavirus among family and health care worker contacts of persons with hantavirus cardiopulmonary syndrome: Lack of evidence for nosocomial transmission of andes virus to health care workers in Chile. American Journal of Tropical Medicine and Hygiene. 2004 Mar;70(3):302-4. PubMed PMID: WOS:000220198800013.
6. Ferres M, Vial P. Hantavirus infection in children. Current Opinion in Pediatrics. 2004 Feb;16(1):70-5. PubMed PMID: WOS:000220641100012.
7. Ortiz JC, Venegas W, Sandoval JA, Chandia P, Torres-Perez F. Hantavirus in rodents of the VIII Region of Chile. Revista Chilena De Historia Natural. 2004 Jun;77(2):251-6. PubMed PMID: WOS:000222808600005
8. Torres-Perez F, Navarrete-Droguett J, Aldunate R, Yates TL, Mertz GJ, Vial PA, et al. Peridomestic small mammals associated with confirmed cases of human hantavirus disease in southcentral Chile. American Journal of Tropical Medicine and Hygiene. 2004 Mar;70(3):305-9. PubMed PMID: WOS:000220198800014.
9. Vial P, Ferres M, Belmar E, Castillo C, Tapia M, Donoso S, et al. Characterization of the hantavirus infection in Chile: Incubation period, clinical presentation and viral load in body fluids in patients with hanta cardiopulmonary syndrome (HCPS). Pediatric Research. 2004 Mar;55(3):528-. PubMed PMID: WOS:000189111000031.
10. Armien B, Pascale JM, Bayard V, Muñoz C, Mosca I, Guerrero G, Armien A, Quiroz E, Castillo Z, Zaldivar Y, Gracia F, Hjelle B, Koster F. HIGH SEROPREVALENCE OF HANTAVIRUS INFECTION ON THE AZUERO PENINSULA OF PANAMA, Am J Trop Med Hyg, 2004, Jun, 70 (6) 682-687, PMID 15211014
11. Lobos G, Ferres M, Palma RE. Presence of the invasive genera Mus and Rattus in natural areas in Chile: an environmental and epidemiological risk. Revista Chilena De Historia Natural. 2005 Mar;78(1):113-24. PubMed PMID: WOS:000228657000008.
12. Spotorno A, Evolutionary medicine:an emergent basic science, Revista Medica de Chile, 2005, Feb; 133:231-40, ISSN: 0034-9887, PMID: 15824835
13. Tomicic V, Espinoza M, Torres J, Abarca J, Montes JM, Luppi M, et al. Addition of an arterio-venous shunt during veno-arterial extracorporeal life support in a patient with Hantavirus pulmonary syndrome. Revista Medica De Chile. 2005 Jul;133(7):817-22. PubMed PMID: WOS:000231654900010.
14. Mertz GJ, Hjelle B, Crowley M, Iwamoto G, Tomicic V, Vial PA. Diagnosis and treatment of new world hantavirus infections. Current Opinion in Infectious Diseases. 2006 Oct;19(5):437-42. PubMed PMID: WOS:000240898600006.
15. Schmidt J, Meisel H, Capria SG, Petraityte R, Lundkvist A, Hjelle B, et al. Serological assays for the detection of human Andes hantavirus infections based on its yeast-expressed nucleocapsid protein. Intervirology. 2006 2006;49(3):173-84. PubMed PMID: WOS:000234829200007.
16. Valdivieso F, Vial P, Ferres M, Ye CY, Goade D, Cuiza A, et al. Neutralizing antibodies in survivors of Sin Nombre and Andes hantavirus infection. Emerging Infectious Diseases. 2006 Jan;12(1):166-8. PubMed PMID: WOS:000234419700033.
17. Vial PA, Valdivieso F, Mertz G, Castillo C, Belmar E, Delgado I, et al. Incubation period of hantavirus cardiopulmonary syndrome. Emerging Infectious Diseases. 2006 Aug;12(8):1271-3. PubMed PMID: WOS:000239358500019.
18. Vigil JR, Ferres M, Nofchissey RA, Pierce AA, Goade DE. The humoral immune response during the acute and convalescent phase of hantavirus infection in children. Journal of Investigative Medicine. 2006 Jan;54(1):S133-S. PubMed PMID: WOS:000235301500324.
19. Ferrer C P, Vial C PA, Ferres G M, Godoy M P, Cuiza V A, Marco C C, et al. Genetic susceptibility to Andes Hantavirus: Association between severity of disease and HLA alleles in Chilean patients. Revista Chilena De Infectologia. 2007 Oct;24(5):351-9. PubMed PMID: WOS:000254581500001.
20. Ferres M, Vial P, Marco C, Yanez L, Godoy P, Castillo C, Hjelle B, Delgado I, Lee SJ, Mertz GJ; Andes Virus Household Contacts Study Group. Prospective evaluation of household contacts of persons with hantavirus cardiopulmonary sindrome in Chile. J Infect Dis. 2007 Jun 1;195(11):1563-71.Epub 2007 Apr16. PubMed PMID:17471425
21. Glass GE, Marquet PA, Palma ER, Barria I, Yates TL, Vial PA, et al. PREDICTING HANTAVIRUS RISK IN CHILE. American Journal of Tropical Medicine and Hygiene. 2008 Dec;79(6):210-. PubMed PMID: WOS:000261644601078.
22. Godoy P, Stefas E, Ferrer P, Vollrath V, Vial P, Ferres M, et al. ApOH-capture technology enhances Andes hantavirus detection allowing virus concentration from plasma and urine samples of patients with acute hantavirus cardiopulmonary syndrome. Infection Genetics and Evolution. 2008 Jul;8(4):S14-S5. PubMed PMID: WOS:000257001400051.
23. Manigold T, Martinez J, Lazcano X, Ye C, Schwartz S, Cuiza A, et al. Case report: T-cell responses during clearance of Andes virus from blood cells 2 months after severe Hantavirus Cardiopulmonary syndrome. Journal of Medical Virology. 2008 Nov;80(11):1947-51. PubMed PMID: WOS:000259622800012.
24. Pablo VA, Ferres M, Valdivieso F, Delgado I, Calvo M, Castillo C, et al. CLINICAL COURSE OF HANTAVIRUS CARDIOPULMONARY SYNDROME IN CHILEAN PATIENTS. American Journal of Tropical Medicine and Hygiene. 2008 Dec;79(6):330-. PubMed PMID: WOS:000261644601490.
25. Pablo VA, Mertz GJ, Ferres M, Galeno H, Belmar E, Aldunate R, et al. ANDES VIRAL RNA LOAD IN CHILEAN PATIENTS WITH HANTAVIRUS CARDIOPULMONARY SYNDROME. American Journal of Tropical Medicine and Hygiene. 2008 Dec;79(6):323-. PubMed PMID: WOS:000261644601466.
26. Godoy P, Marsac D, Stefas E, Ferrer P, Tischler ND, Pino K, et al. Andes Virus Antigens Are Shed in Urine of Patients with Acute Hantavirus Cardiopulmonary Syndrome. Journal of Virology. 2009 May 15;83(10):5046-55. PubMed PMID: WOS:000265407700031.
27. Belmar-Lucero S, Godoy P, Ferres M, Vial P, Eduardo Palma R. Range expansion of Oligoryzomys longicaudatus (Rodentia, Sigmodontinae) in Patagonian Chile, and first record of Hantavirus in the region. Revista Chilena De Historia Natural. 2009 Jun;82(2):265-75. PubMed PMID: WOS:000268550000008.
28. Medina RA, Torres-Perez F, Galeno H, Navarrete M, Vial PA, Palma RE, et al. Ecology, Genetic Diversity, and Phylogeographic Structure of Andes Virus in Humans and Rodents in Chile. Journal of Virology. 2009 Mar 15;83(6):2446-59. PubMed PMID: WOS:000263650500005.
29. Ferres G M, Sandoval C C, Delgado B I, Sotomayor P V, Olea N A, Vial C PA. Hantavirosis: Clinical and epidemiological characteristics of pediatric patients in Chile. Revista Chilena De Infectologia. 2010 Feb;27(1):52-9. PubMed PMID: WOS:000274068100009.
30. Manigold T, Mori A, Graumann R, Llop E, Simon V, Ferres M, et al. Highly Differentiated, Resting Gn-Specific Memory CD8(+) T Cells Persist Years after Infection by Andes Hantavirus. Plos Pathogens. 2010 Feb;6(2). PubMed PMID: WOS:000275295900029.
31. Torres-Perez F, Eduardo Palma R, Hjelle B, Ferres M, Cook JA. Andes virus infections in the rodent reservoir and in humans vary across contrasting landscapes in Chile. Infection Genetics and Evolution. 2010 Aug;10(6):820-5. PubMed PMID: WOS:000280116400018.
32. Vera-Otarola J, Soto-Rifo R, Ricci EP, Ohlmann T, Darlix J-L, Lopez-Lastra M. The 3 ' Untranslated Region of the Andes Hantavirus Small mRNA Functionally Replaces the Poly(A) Tail and Stimulates Cap-Dependent Translation Initiation from the Viral mRNA. Journal of Virology. 2010 Oct;84(19):10420-4. PubMed PMID: WOS:000282641800073.
33. Marsac D, Garcia S, Fournet A, Aguirre A, Pino K, Ferres M, et al. Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances proinflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability. Virology Journal. 2011 May 13;8. PubMed PMID: WOS:000291103500001.
34. Torres-Perez F, Eduardo Palma R, Hjelle B, Holmes EC, Cook JA. Spatial but not temporal co-divergence of a virus and its mammalian host. Molecular Ecology. 2011 Oct;20(19):4109-22. PubMed PMID: WOS:000295230000014.
35. Boric-Bargetto D, Rodriguez-Serrano E, Hernandez CE, Jaksic FM, Eduardo Palma R. Temporal variation in genetic diversity during an outbreak of Oligoryzomys longicaudatus (Rodentia, Sigmodontinae) in a temperate forest of southern Chile. Biochemical Systematics and Ecology. 2012 Oct;44:383-9. PubMed PMID: WOS:000307692100064.
36. Brocato R, Josleyn M, Ballantyne J, Vial P, Hooper JW. DNA Vaccine-Generated Duck Polyclonal Antibodies as a Postexposure Prophylactic to Prevent Hantavirus Pulmonary Syndrome (HPS). Plos One. 2012 Apr 27;7(4). PubMed PMID: WOS:000305336000097.
37. Eduardo Palma R, Boric-Bargetto D, Torres-Perez F, Hernandez CE, Yates TL. Glaciation Effects on the Phylogeographic Structure of Oligoryzomys longicaudatus (Rodentia: Sigmodontinae) in the Southern Andes. Plos One. 2012 Mar 1;7(3). PubMed PMID: WOS:000303005000017.
38. Palma RE, Polop JJ, Owen RD, Mills JN. ECOLOGY OF RODENT-ASSOCIATED HANTAVIRUSES IN THE SOUTHERN CONE OF SOUTH AMERICA: ARGENTINA, CHILE, PARAGUAY, AND URUGUAY. Journal of Wildlife Diseases. 2012 Apr;48(2):267-81. PubMed PMID: WOS:000302589000002.
39. Schountz T, Acuna-Retamar M, Feinstein S, Prescott J, Torres-Perez F, Podell B, et al. Kinetics of Immune Responses in Deer Mice Experimentally Infected with Sin Nombre Virus. Journal of Virology. 2012 Sep;86(18):10015-27. PubMed PMID: WOS:000308337500043.
40. Vera-Otarola J, Solis L, Soto-Rifo R, Ricci EP, Pino K, Tischler ND, et al. The Andes Hantavirus NSs Protein Is Expressed from the Viral Small mRNA by a Leaky Scanning Mechanism. Journal of Virology. 2012 Feb;86(4):2176-87. PubMed PMID: WOS:000299862500026.
41. Barriga GP, Martinez-Valdebenito C, Galeno H, Ferres M, Lozach P-Y, Tischler ND. A rapid method for infectivity titration of Andes hantavirus using flow cytometry. Journal of Virological Methods. 2013 Nov;193(2):291-4. PubMed PMID: WOS:000325190400005.
42. Lederer S, Lattwein E, Hanke M, Sonnenberg K, Stoecker W, Lundkvist A, et al. Indirect Immunofluorescence Assay for the Simultaneous Detection of Antibodies against Clinically Important Old and New World Hantaviruses. Plos Neglected Tropical Diseases. 2013 Apr;7(4). PubMed PMID: WOS:000318153100018.
43. Vial PA, Valdivieso F, Ferres M, Riquelme R, Luisa Rioseco M, Calvo M, et al. High-Dose Intravenous Methylprednisolone for Hantavirus Cardiopulmonary Syndrome in Chile: A Double-Blind, Randomized Controlled Clinical Trial. Clinical Infectious Diseases. 2013 Oct 10;57(7):943-51. PubMed PMID: WOS:000326027400006.
44. Karla Cautivo , Tony Schountz, Mariana Acuña-Retamar , Marcela Ferrés and Fernando Torres-Pérez. Rapid Enzyme-Linked Immunosorbent Assay for the Detection of Hantavirus-Specific Antibodies in Divergent Small Mammals. Viruses .2014, 6(5), 2028-2037; doi:10.3390/v6052028.
45. Martinez-Valdebenito C, Calvo M, Vial C, Mansilla R, Marco C, Palma RE, Valdivieso F, Vial PA, Mertz GJ, Ferres M.Person to person household and nosocomial transmission of Andes hantavirus, Southern Chile, 2011. EID 2014 Vol. 20, no.10, October, 2014,http://wwwnc.cdc.gov/eid/article/20/10/14-0353_article.htm
46. Vial PA, Valdivieso F, Calvo M, Rioseco ML, Riquelme R, Araneda A, Tomicic V, Graf J, Paredes L, Florenzano M, Bidart T, Ferres M, Cuiza A, Marco C, Hjelle B, Ye C, Hanfelt-Goade D, Vial C, Rivera JC, Delgado I, Mertz GJ. A nonrandomized multicenter trial of human immune plasma for treatment of hantavirus
47. Riquelme R, Rioseco ML, Bastidas L, Trincado D, Riquelme M, Loyola H, et al. Hantavirus pulmonary syndrome, southern Chile, 1995–2012. Emerg Infect Dis [Internet]. 2015 Apr http://dx.doi.org/10.3201/eid2104.141437
48. A nonrandomized multicenter trial of human immune plasma for treatment of hantavirus cardiopulmonary syndrome by ANDV, Vial Pablo, Valdivieso Francisca, Calvo Mario, Rioseco Maria Luisa, Riquelme Raúl, Araneda Andres, Tomicic Vinko, Graf Jerónimo, Paredes Laura, Florenzano Matias, Bidart Teresa, Cuiza Analia, Marco Claudia, Hjelle Brian, Ye Chunyan, Hanfelt-Goade Diane, Vial Cecilia, Rivera Juan Carlos, Delgado Iris, Mertz Gregory J. Hantavirus Study Group in Chile, Antiviral Therapy, 2015, doi: 10.3851/IMP2875.
49. Susana Eyheramendy, Felipe I Martinez, Federico Manevy, Cecilia Vial*, Gabriela M Repetto, Genetic structure characterization of Chileans reflects historical immigration patterns, Nat Comm, 2015, 6:6472: 1-10, DOI: 10.1038/ncomms7472
50. Cecilia Vial*, Constanza Martinez-Valdebenito, Susana Rios, Jessica Martinez, Pablo A. Vial, Marcela Ferres, Juan C.Rivera, Ruth Perez, Francisca Valdivieso, Molecular method for the detection of Andes hantavirus infection: validation for clinical diagnostics, DMID, 2016, 84 (1): 36–39.
51. Hemodynamic and Pulmonary Permeability Characterization of Hantavirus Cardiopulmonary Syndrome by Transpulmonary Thermodilution, by René López , Rodrigo Pérez-Araos , Álvaro Salazar, Ana L. Ulloa , Cecilia Vial ,Pablo A. Vial and Jerónimo Graf, Viruses 2019, 11(10), 900; https://doi.org/10.3390/v11100900
52. A 19 Year Analysis of Small Mammals Associated with Human Hantavirus Cases in Chile, Fernando Torres-Pérez, R. Eduardo Palma ,Dusan Boric-Bargetto ,Cecilia Vial, Marcela Ferrés ,Pablo A. Vial ,Constanza Martínez-Valdebenito ,Carlos Pavletic, Alonso Parra, Pablo A. Marquet and Gregory J. Mertz, Viruses 2019, 11(9), 848; https://doi.org/10.3390/v11090848
53. Platelet Count in Patients with Mild Disease at Admission is Associated with Progression to Severe Hantavirus Cardiopulmonary Syndrome, René López, Cecilia Vial , Jerónimo Graf, Mario Calvo, Marcela Ferrés , Gregory Mertz , Analía Cuiza , Begonia Agüero, Dante Aguilera, Diego Araya, Ignacia Pailamilla ,Flavia Paratori,Víctor Torres-Torres,Pablo A Vial and Hantavirus Study Group in Chile, Viruses 2019, 11(8), 693; https://doi.org/10.3390/v11080693
54. Deletions in Genes Participating in Innate Immune Response Modify the Clinical Course of Andes Orthohantavirus Infection, Grazielle Esteves Ribeiro ,Luis Edgardo Leon ,Ruth Perez, Analia Cuiza ,Pablo Agustin Vial, Marcela Ferres ,Gregory J. Mertz and Cecilia Vial *, Viruses 2019, 11(8), 680; https://doi.org/10.3390/v11080680
55. Factores de riesgo sociodemográficos del síndrome cardiopulmonar por hantavirus, *Cecilia Vial C., Francisca Valdivieso R., Analía Cuiza V., Iris Delgado B., Grazielle Ribeiro E.,Elena Llop R., Marcela Ferrés G. Gabriela M. Repetto L., Raúl Riquelme, Maria Luisa Rioseco , Mario Calvo, Gregory Mertz, Pablo A. Vial C., Revista Chilena de Infectologia, 36 (4):428., 2019
56. A Single-Nucleotide Polymorphism of αVβ3 Integrin Is Associated with the Andes Virus Infection Susceptibility, C Constanza Martínez-Valdebenito, Jenniffer Angulo, Nicole Le Corre, Claudia Marco, Cecilia Vial, Juan Francisco Miquel, Jaime Cerda, Gregory Mertz, Pablo Vial, Marcelo Lopez-Lastra, Marcela Ferrés, Viruses 2019 11 (2):169, https://doi.org/10.3390/v11020169